The Scientific activity of the group is focused on the application and development of experimental and computational techniques for the investigation of the structure and dynamics of macromolecules of biological interest. Our main experimental expertise is on the use of X-ray spectroscopy both at Synchrotrons and at the newly available FEL facilities. Advanced computational methods, ranging from classical molecular dynamics to DFT and Car-Parrinello type simulations, are employed to help interpreting experimental data and modelling biomolecular structures.